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Great new General Urologist need with Laparoscopic experience needed in West Virginia! :: West Virginia :: CompHealth Inc
Job 919850 Great new General Urologist need with Laparoscopic experience needed in West Virginia! Join a Hospital as an employed physician with a productivity based model. Share call 1:3 with two other
Opportunity for a Urologist to take over a Successful Urology Practice in Texas!! :: Texas :: CompHealth Inc
Job 919831 General Urology. Robotics Available if Desired. Candidates must be BC/BE. Urologist who is retiring sees approximately 100 patients per week and does 30-40 cases per month! Call shared
Urologist needed to join a great practice in Northern California. :: California :: CompHealth Inc
Job 9110238 Join stable, successful practice, or be solo. Join a great practice with two clinics. Nice mix of clinic and surgeries, as well as strong referral network. Hospital system is very supportive
Urology / Nephrology News From Medical News Today
European Medicines Agency Makes Recommendations To Minimise Risk Of Nephrogenic Systemic Fibrosis With Gadolinium-containing Contrast Agents
Sun, 22 Nov 2009 00:00:00 -0800
The European Medicines Agency (EMEA) has adopted a set of recommendations aimed at minimising the risk of nephrogenic systemic fibrosis (NSF) with gadolinium-containing contrast agents in patients at risk of developing the condition. Gadolinium-containing contrast agents are used in patients undergoing magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA) scans.
High Blood Pressure Easy To Miss In Children With Kidney Disease
Sat, 21 Nov 2009 01:00:00 -0800
Spot blood pressure readings in children with chronic kidney disease often fail to detect hypertension even during doctor's office visits increasing a child's risk for serious heart problems, according to research from Johns Hopkins Children's Center and other institutions. A report of the findings appears online in the Journal of American Society of Nephrology.
Heart Disease In Kidney Transplant Patients May Be Caused By Sleep Apnea
Sat, 21 Nov 2009 00:00:00 -0800
Sleep apnea is common in individuals who receive a kidney transplant and is associated with increased risk of high blood pressure, heart disease or stroke, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Researchers found that kidney transplant patients are just as likely to have this sleep disorder as dialyzed kidney disease patients who are on the transplant waiting list.
BMC Urology - Latest Articles
Treatment success for overactive bladder with urinary urge incontinence refractory to oral antimuscarinics: a review of published evidence
Jonathan CampbellKatharine GriesJonathan WatanabeArliene RaveloRoger DmochowskiSean Sullivan Fri, 20 Nov 2009 00:00:00 -0000
Background: Treatment options for overactive bladder (OAB) with urinary urge incontinence (UUI) refractory to oral antimuscarinics include: botulinum toxin type A (BoNTA), sacral neuromodulation (SNM), and augmentation cystoplasty (AC). A standard treatment success metric that can be used in both clinical and economic evaluations of the above interventions has not emerged. Our objective was to conduct a literature review and synthesis of published measures of treatment success for OAB with UUI interventions and to identify a treatment success outcome. Methods: We performed a literature review of primary studies that used a definition of treatment success in the OAB with UUI population receiving BoNTA, SNM, or AC. The recommended success outcome was compared to generic and disease-specific health-related quality-of-life (HRQoL) measures using data from a BoNTA treatment study of neurogenic incontinent patients. Results: Across all interventions, success outcomes included: complete continence (n=23, 44%), >=50% improvement in incontinence episodes (n=16, 31%), and subjective improvement (n=13, 25%). We recommend the OAB with UUI treatment success outcome of >=50% improvement in incontinence episodes from baseline. Using data from a neurogenic BoNTA treatment study, the average change in the Incontinence Quality of Life questionnaire was 8.8 (95% CI: -4.7, 22.3) higher for those that succeeded (N=25) versus those that failed (N=26). The average change in the SF-6D preference score was 0.07 (95% CI: 0.02, 0.12) higher for those that succeeded versus those that failed. Conclusions: A treatment success definition that encompasses the many components of underlying OAB with UUI symptoms is currently not practical as a consequence of difficulties in measuring urgency. The treatment success outcome of >=50% improvement in incontinence episodes was associated with a clinically meaningful improvement in disease-specific HRQoL for those with neurogenic OAB with UUI. The recommended success definition is less restrictive than a measure such as complete continence but includes patients who are satisfied with treatment and experience meaningful improvement in symptoms. A standardized measure of treatment success will be useful in clinical and health economic applications.
Percutaneous nephrolithotomy in horseshoe Kidneys: is rigid nephroscopy sufficient tool for complete clearance? a case series study
Mohamed El GhoneimyAhmed KoderaAshraf EmranTamer OrbanAhmed ShabanMohamed El Gammal Mon, 16 Nov 2009 00:00:00 -0000
Background: this study represents a case series to evaluate how successful is the rigid percutaneous nephroscopy as a tool for clearance of all stones in various locations in horseshoe kidneys. Methods: Between 2005 and 2009, we carried out PCNL (percutaneous nephrolithotomy) for calculi in horseshoe kidneys in 21 renal units (17 patients) in our department. The indications were large stone burden in 18 units and failed SWL( shock wave lithotripsy) in 3 renal units. All procedures were done under general anesthesia; using fluoroscopic guidance for localization and standard alkan dilatation followed by rigid nephroscopy and stone extraction with or without stone disintegration. We analyzed our results regarding the site and number of the required access, the intra and postoperative complications, the presence of any residual stones, as well as their location. Results: The procedure was completed, using a single access tract in 20 renal units, with the site of puncture being the upper calyx in nine units and the posterior middle calyx in eleven units. Only in one renal unit, two access tracts (an upper and a lower calyceal) were required for completion and a supracostal puncture was required in another case. There was no significant intraoperative bleeding and no blood transfusion was required in any patient. A pelvic perforation occurred in one case, requiring longer PCN (percutaneous nephrostomy) drainage. One patient with infection stones suffered urosepsis postoperatively which was successfully managed. Three cases had residual stones, all located in the renal isthmus, all residuals were un approachable with the rigid instrument; resulting in a overall stone-free rate of 85.7 % at discharge. Conclusion: Percutaneous nephrolithotomy is generally safe and successful in the management of stones in horseshoe kidneys. However, location of the stones in these patients is crucial to decide the proper tool for optimal stone clearance result.
Pharmacologic attenuation of pelvic pain in a Murine model of interstitial cystitis
Charles RudickAnthony SchaefferDavid Klumpp Thu, 12 Nov 2009 00:00:00 -0000
Background: Interstitial cystitis/painful bladder syndrome (IC/PBS) is a bladder disease that causes debilitating pelvic pain of unknown origin, and IC/PBS symptoms correlate with elevated bladder lamina propria mast cell counts. Similar to IC/PBS patients, pseudorabies virus (PRV) infection in mice induces a neurogenic cystitis associated with bladder lamina propria mast cell accumulation and pelvic pain. We evaluated several drugs to determine the effectiveness of reducing PRV-induced pelvic pain. Methods: Neurogenic cystitis was induced by the injection of Bartha's strain of PRVinto the abductor caudalis dorsalis tail base muscle of female C57BL/6 mice. Therapeutic modulation of pelvic pain was assessed daily for five days using von Frey filament stimulation to the pelvic region to quantify tactile allodynia. Results: Significant reduction of PRV-induced pelvic pain was observed for animals treated with antagonists of neurokinin receptor 1 and histamine receptors. In contrast, the H1R antagonist hydroxyzine, proton pump inhibitors, a histamine receptor 3 agonist, and gabapentin had little or no effect on PRV-induced pelvic pain. Conclusions: These data demonstrate that bladder-associated pelvic pain is attenuated by antagonists of NK1R, H2R, and H1R. Therefore, NK1R, H2R and H1R represent direct therapeutic targets for pain in IC/PBS and potentially other chronic pain conditions.
Donor site morbidity in oral mucosa graft urethroplasty: implications of tobacco consumption
Rahul Janak SinhaVishwajeet SinghS SankhwarDivakar Dalela Mon, 21 Sep 2009 00:00:00 -0000
Background: The purpose of this prospective study was to evaluate the donor site morbidity in patients who have undergone oral mucosa graft urethroplasty for stricture of the urethra. The impact of smoking and oral consumption of tobacco and/or paan masala on the donor site was also assessed. This study is probably the first of its kind where the affect of smoking, paan masala and tobacco chewing on the donor site morbidity has been documented. Methods: Forty-eight patients suffering from stricture of the urethra underwent oral mucosa graft urethroplasty between July 2005 and December 2007. The patients were divided into two groups (users or non-users) based on tobacco consumption and oral hygiene. The donor site was evaluated at frequent intervals for pain, swelling, numbness, bleeding, salivation and tightness of mouth. Results: Donor site morbidity was more in users with poor oral hygiene. Pain scores were higher amongst the users and the morbidity persisted longer in the users compared to non-users with good oral hygiene. Conclusion: Patients who consume tobacco and have poor oral hygiene should be warned regarding poorer outcomes after oral mucosa graft urethroplasty.
A systematic review of the diagnostic accuracy of prostate specific antigen
Philip HarveyAmman BasuitaDeborah EndersbyBen CurtisAphrodite IacovidouMary Walker Thu, 10 Sep 2009 00:00:00 -0000
Background: Prostate cancer is the fourth commonest cancer in the UK, and the incidence is rising. The reference standard for diagnosing this condition is prostate biopsy, an invasive procedure.This study systematically reviews recent literature on tPSA accuracy. The time period was restricted to ensure that the estimates referred to contemporary tPSA tests and prostate cancer reference standards. The focus of this review was restricted to European populations as tPSA levels are known to vary by population group. Methods: Medline was searched (from 01/1998 to 01/2008) and Embase (from 01/1998 to 01/2008), which returned 3087 citations. These were assessed by 6 reviewers, who shortlisted 54 of possible relevance. 2 reviewers assessed each using the following inclusion criteria: data collection between 1998-2008; tPSA measurements for all participants; histological confirmation of the diagnosis; samples from a European population and sufficient data to calculate 2 × 2 tables. The final set of 10 included studies represented 5373 participants. Quality of the included studies was assessed in duplicate using criteria suggested by the Cochrane Collaboration. Review Manager 5.0 software was used to analyse the data, including plotting a series of summary receiver operator curve spaces (SROC). Results: tPSA sensitivities ranged from 0.78 to 1.00 and specificities from 0.06 to 0.66. Positive likelihood ratios ranged from 0.83 to 2.90 and negative likelihood ratios ranged from 0.00 to 3.75 Conclusion: tPSA ha
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Great new General Urologist need with Laparoscopic experience needed in West Virginia! :: West Virginia :: CompHealth Inc
Job 919850 Great new General Urologist need with Laparoscopic experience needed in West Virginia! Join a Hospital as an employed physician with a productivity based model. Share call 1:3 with two other
Opportunity for a Urologist to take over a Successful Urology Practice in Texas!! :: Texas :: CompHealth Inc
Job 919831 General Urology. Robotics Available if Desired. Candidates must be BC/BE. Urologist who is retiring sees approximately 100 patients per week and does 30-40 cases per month! Call shared
Urologist needed to join a great practice in Northern California. :: California :: CompHealth Inc
Job 9110238 Join stable, successful practice, or be solo. Join a great practice with two clinics. Nice mix of clinic and surgeries, as well as strong referral network. Hospital system is very supportive
Urology / Nephrology News From Medical News Today
European Medicines Agency Makes Recommendations To Minimise Risk Of Nephrogenic Systemic Fibrosis With Gadolinium-containing Contrast Agents
Sun, 22 Nov 2009 00:00:00 -0800
The European Medicines Agency (EMEA) has adopted a set of recommendations aimed at minimising the risk of nephrogenic systemic fibrosis (NSF) with gadolinium-containing contrast agents in patients at risk of developing the condition. Gadolinium-containing contrast agents are used in patients undergoing magnetic resonance imaging (MRI) or magnetic resonance angiography (MRA) scans.
High Blood Pressure Easy To Miss In Children With Kidney Disease
Sat, 21 Nov 2009 01:00:00 -0800
Spot blood pressure readings in children with chronic kidney disease often fail to detect hypertension even during doctor's office visits increasing a child's risk for serious heart problems, according to research from Johns Hopkins Children's Center and other institutions. A report of the findings appears online in the Journal of American Society of Nephrology.
Heart Disease In Kidney Transplant Patients May Be Caused By Sleep Apnea
Sat, 21 Nov 2009 00:00:00 -0800
Sleep apnea is common in individuals who receive a kidney transplant and is associated with increased risk of high blood pressure, heart disease or stroke, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Researchers found that kidney transplant patients are just as likely to have this sleep disorder as dialyzed kidney disease patients who are on the transplant waiting list.
BMC Urology - Latest Articles
Treatment success for overactive bladder with urinary urge incontinence refractory to oral antimuscarinics: a review of published evidence
Jonathan CampbellKatharine GriesJonathan WatanabeArliene RaveloRoger DmochowskiSean Sullivan Fri, 20 Nov 2009 00:00:00 -0000
Background: Treatment options for overactive bladder (OAB) with urinary urge incontinence (UUI) refractory to oral antimuscarinics include: botulinum toxin type A (BoNTA), sacral neuromodulation (SNM), and augmentation cystoplasty (AC). A standard treatment success metric that can be used in both clinical and economic evaluations of the above interventions has not emerged. Our objective was to conduct a literature review and synthesis of published measures of treatment success for OAB with UUI interventions and to identify a treatment success outcome. Methods: We performed a literature review of primary studies that used a definition of treatment success in the OAB with UUI population receiving BoNTA, SNM, or AC. The recommended success outcome was compared to generic and disease-specific health-related quality-of-life (HRQoL) measures using data from a BoNTA treatment study of neurogenic incontinent patients. Results: Across all interventions, success outcomes included: complete continence (n=23, 44%), >=50% improvement in incontinence episodes (n=16, 31%), and subjective improvement (n=13, 25%). We recommend the OAB with UUI treatment success outcome of >=50% improvement in incontinence episodes from baseline. Using data from a neurogenic BoNTA treatment study, the average change in the Incontinence Quality of Life questionnaire was 8.8 (95% CI: -4.7, 22.3) higher for those that succeeded (N=25) versus those that failed (N=26). The average change in the SF-6D preference score was 0.07 (95% CI: 0.02, 0.12) higher for those that succeeded versus those that failed. Conclusions: A treatment success definition that encompasses the many components of underlying OAB with UUI symptoms is currently not practical as a consequence of difficulties in measuring urgency. The treatment success outcome of >=50% improvement in incontinence episodes was associated with a clinically meaningful improvement in disease-specific HRQoL for those with neurogenic OAB with UUI. The recommended success definition is less restrictive than a measure such as complete continence but includes patients who are satisfied with treatment and experience meaningful improvement in symptoms. A standardized measure of treatment success will be useful in clinical and health economic applications.
Percutaneous nephrolithotomy in horseshoe Kidneys: is rigid nephroscopy sufficient tool for complete clearance? a case series study
Mohamed El GhoneimyAhmed KoderaAshraf EmranTamer OrbanAhmed ShabanMohamed El Gammal Mon, 16 Nov 2009 00:00:00 -0000
Background: this study represents a case series to evaluate how successful is the rigid percutaneous nephroscopy as a tool for clearance of all stones in various locations in horseshoe kidneys. Methods: Between 2005 and 2009, we carried out PCNL (percutaneous nephrolithotomy) for calculi in horseshoe kidneys in 21 renal units (17 patients) in our department. The indications were large stone burden in 18 units and failed SWL( shock wave lithotripsy) in 3 renal units. All procedures were done under general anesthesia; using fluoroscopic guidance for localization and standard alkan dilatation followed by rigid nephroscopy and stone extraction with or without stone disintegration. We analyzed our results regarding the site and number of the required access, the intra and postoperative complications, the presence of any residual stones, as well as their location. Results: The procedure was completed, using a single access tract in 20 renal units, with the site of puncture being the upper calyx in nine units and the posterior middle calyx in eleven units. Only in one renal unit, two access tracts (an upper and a lower calyceal) were required for completion and a supracostal puncture was required in another case. There was no significant intraoperative bleeding and no blood transfusion was required in any patient. A pelvic perforation occurred in one case, requiring longer PCN (percutaneous nephrostomy) drainage. One patient with infection stones suffered urosepsis postoperatively which was successfully managed. Three cases had residual stones, all located in the renal isthmus, all residuals were un approachable with the rigid instrument; resulting in a overall stone-free rate of 85.7 % at discharge. Conclusion: Percutaneous nephrolithotomy is generally safe and successful in the management of stones in horseshoe kidneys. However, location of the stones in these patients is crucial to decide the proper tool for optimal stone clearance result.
Pharmacologic attenuation of pelvic pain in a Murine model of interstitial cystitis
Charles RudickAnthony SchaefferDavid Klumpp Thu, 12 Nov 2009 00:00:00 -0000
Background: Interstitial cystitis/painful bladder syndrome (IC/PBS) is a bladder disease that causes debilitating pelvic pain of unknown origin, and IC/PBS symptoms correlate with elevated bladder lamina propria mast cell counts. Similar to IC/PBS patients, pseudorabies virus (PRV) infection in mice induces a neurogenic cystitis associated with bladder lamina propria mast cell accumulation and pelvic pain. We evaluated several drugs to determine the effectiveness of reducing PRV-induced pelvic pain. Methods: Neurogenic cystitis was induced by the injection of Bartha's strain of PRVinto the abductor caudalis dorsalis tail base muscle of female C57BL/6 mice. Therapeutic modulation of pelvic pain was assessed daily for five days using von Frey filament stimulation to the pelvic region to quantify tactile allodynia. Results: Significant reduction of PRV-induced pelvic pain was observed for animals treated with antagonists of neurokinin receptor 1 and histamine receptors. In contrast, the H1R antagonist hydroxyzine, proton pump inhibitors, a histamine receptor 3 agonist, and gabapentin had little or no effect on PRV-induced pelvic pain. Conclusions: These data demonstrate that bladder-associated pelvic pain is attenuated by antagonists of NK1R, H2R, and H1R. Therefore, NK1R, H2R and H1R represent direct therapeutic targets for pain in IC/PBS and potentially other chronic pain conditions.
Donor site morbidity in oral mucosa graft urethroplasty: implications of tobacco consumption
Rahul Janak SinhaVishwajeet SinghS SankhwarDivakar Dalela Mon, 21 Sep 2009 00:00:00 -0000
Background: The purpose of this prospective study was to evaluate the donor site morbidity in patients who have undergone oral mucosa graft urethroplasty for stricture of the urethra. The impact of smoking and oral consumption of tobacco and/or paan masala on the donor site was also assessed. This study is probably the first of its kind where the affect of smoking, paan masala and tobacco chewing on the donor site morbidity has been documented. Methods: Forty-eight patients suffering from stricture of the urethra underwent oral mucosa graft urethroplasty between July 2005 and December 2007. The patients were divided into two groups (users or non-users) based on tobacco consumption and oral hygiene. The donor site was evaluated at frequent intervals for pain, swelling, numbness, bleeding, salivation and tightness of mouth. Results: Donor site morbidity was more in users with poor oral hygiene. Pain scores were higher amongst the users and the morbidity persisted longer in the users compared to non-users with good oral hygiene. Conclusion: Patients who consume tobacco and have poor oral hygiene should be warned regarding poorer outcomes after oral mucosa graft urethroplasty.
A systematic review of the diagnostic accuracy of prostate specific antigen
Philip HarveyAmman BasuitaDeborah EndersbyBen CurtisAphrodite IacovidouMary Walker Thu, 10 Sep 2009 00:00:00 -0000
Background: Prostate cancer is the fourth commonest cancer in the UK, and the incidence is rising. The reference standard for diagnosing this condition is prostate biopsy, an invasive procedure.This study systematically reviews recent literature on tPSA accuracy. The time period was restricted to ensure that the estimates referred to contemporary tPSA tests and prostate cancer reference standards. The focus of this review was restricted to European populations as tPSA levels are known to vary by population group. Methods: Medline was searched (from 01/1998 to 01/2008) and Embase (from 01/1998 to 01/2008), which returned 3087 citations. These were assessed by 6 reviewers, who shortlisted 54 of possible relevance. 2 reviewers assessed each using the following inclusion criteria: data collection between 1998-2008; tPSA measurements for all participants; histological confirmation of the diagnosis; samples from a European population and sufficient data to calculate 2 × 2 tables. The final set of 10 included studies represented 5373 participants. Quality of the included studies was assessed in duplicate using criteria suggested by the Cochrane Collaboration. Review Manager 5.0 software was used to analyse the data, including plotting a series of summary receiver operator curve spaces (SROC). Results: tPSA sensitivities ranged from 0.78 to 1.00 and specificities from 0.06 to 0.66. Positive likelihood ratios ranged from 0.83 to 2.90 and negative likelihood ratios ranged from 0.00 to 3.75 Conclusion: tPSA ha
Sites:
About Urology: Search the power of About's network of topicsDitropan XL: DITROPAN XL (oxybutynin chloride) reduces syptoms of overactive bladder and frequent urination.
DrRajMD.com: DrRajMD.com, providing physician (Dr. Gene Rajaratnam) monitored information on all major urological topis, such as Prostate Cancer, BPH, Prostate Ultrasound and Biopsy, Prostate Conditions, Acute Bacterial Prostatitis, Prostate Cancer, Removal of the Prostate, Kidney Stones, Kidney Cancer, Male...
Global Lithotripsy Services: A Lithotripsy (ESWL, ESWT) Service Provider
Muljibhai Patel Urological Hospital: MPUH is one of its kind in Asia and the first hospital in the country devoted entirely to Nephrology and Urology. Includes information about services, training, research and case studies.
University of Maryland Urologic Surgery Division: Offers a clear and comprehensive explanation of urinary system anatomy and diseases such as kidney stones and impotence with links to related Medical Center services.
Urology Department at Loyola University Medical Center: The Department of Urology at Loyola University Chicago provides a full range of services for children and adults with concerns or problems of the urinary tract or male reproductive system.
Urology jobs: Urology jobs board with automatic email updates with a directory of recruitment firms.
This directory is based on the Open Directory and may have been modified
