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American Journal of Epidemiology - current issue
Cover
Fri, 03 Feb 2012 07:15:44 -0800
Editorial Board
Fri, 03 Feb 2012 07:15:44 -0800
Subscriptions
Fri, 03 Feb 2012 07:15:44 -0800
Table of contents
Fri, 03 Feb 2012 07:15:45 -0800
Anti-Mullerian Hormone: A Potential New Tool in Epidemiologic Studies of Female Fecundability
Baird, D. D., Steiner, A. Z. Fri, 03 Feb 2012 07:15:45 -0800
The objective of the present commentary is to suggest that epidemiologists explore the use of anti-Müllerian hormone (AMH) as a new measurement tool in fecundability studies. The authors briefly summarize the advantages and limitations of the 3 current approaches to studies of fecundability. All 3 approaches involve the collection of time-to-pregnancy or attempt-time data, and most are limited to participants who plan their pregnancies. AMH is produced by ovarian follicles during their early growth stages and is measured clinically to assess ovarian reserve (the number of remaining oocytes). Unlike time to pregnancy, serum AMH level can be assessed regardless of pregnancy-attempt status. Measurements are not significantly affected by phase of the menstrual cycle, oral contraceptive use, or early pregnancy. The authors suggest that AMH measurement can be a valuable addition to traditionally designed fecundability studies. In addition, this hormone should be investigated as an independent measure of fecundability in studies that focus on exposures hypothesized to target the ovary.
Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research From a Meta-Analysis of Statins
Danaei, G., Tavakkoli, M., Hernan, M. A. Fri, 03 Feb 2012 07:15:45 -0800
Randomized clinical trials (RCTs) are usually the preferred strategy with which to generate evidence of comparative effectiveness, but conducting an RCT is not always feasible. Though observational studies and RCTs often provide comparable estimates, the questioning of observational analyses has recently intensified because of randomized-observational discrepancies regarding the effect of postmenopausal hormone replacement therapy on coronary heart disease. Reanalyses of observational data that excluded prevalent users of hormone replacement therapy led to attenuated discrepancies, which begs the question of whether exclusion of prevalent users should be generally recommended. In the current study, the authors evaluated the effect of excluding prevalent users of statins in a meta-analysis of observational studies of persons with cardiovascular disease. The pooled, multivariate-adjusted mortality hazard ratio for statin use was 0.77 (95% confidence interval (CI): 0.65, 0.91) in 4 studies that compared incident users with nonusers, 0.70 (95% CI: 0.64, 0.78) in 13 studies that compared a combination of prevalent and incident users with nonusers, and 0.54 (95% CI: 0.45, 0.66) in 13 studies that compared prevalent users with nonusers. The corresponding hazard ratio from 18 RCTs was 0.84 (95% CI: 0.77, 0.91). It appears that the greater the proportion of prevalent statin users in observational studies, the larger the discrepancy between observational and randomized estimates.
American Journal of Epidemiology - recent issues
Cover
Fri, 03 Feb 2012 07:15:44 -0800
Editorial Board
Fri, 03 Feb 2012 07:15:44 -0800
Subscriptions
Fri, 03 Feb 2012 07:15:44 -0800
Table of contents
Fri, 03 Feb 2012 07:15:45 -0800
Anti-Mullerian Hormone: A Potential New Tool in Epidemiologic Studies of Female Fecundability
Baird, D. D., Steiner, A. Z. Fri, 03 Feb 2012 07:15:45 -0800
The objective of the present commentary is to suggest that epidemiologists explore the use of anti-Müllerian hormone (AMH) as a new measurement tool in fecundability studies. The authors briefly summarize the advantages and limitations of the 3 current approaches to studies of fecundability. All 3 approaches involve the collection of time-to-pregnancy or attempt-time data, and most are limited to participants who plan their pregnancies. AMH is produced by ovarian follicles during their early growth stages and is measured clinically to assess ovarian reserve (the number of remaining oocytes). Unlike time to pregnancy, serum AMH level can be assessed regardless of pregnancy-attempt status. Measurements are not significantly affected by phase of the menstrual cycle, oral contraceptive use, or early pregnancy. The authors suggest that AMH measurement can be a valuable addition to traditionally designed fecundability studies. In addition, this hormone should be investigated as an independent measure of fecundability in studies that focus on exposures hypothesized to target the ovary.
Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research From a Meta-Analysis of Statins
Danaei, G., Tavakkoli, M., Hernan, M. A. Fri, 03 Feb 2012 07:15:45 -0800
Randomized clinical trials (RCTs) are usually the preferred strategy with which to generate evidence of comparative effectiveness, but conducting an RCT is not always feasible. Though observational studies and RCTs often provide comparable estimates, the questioning of observational analyses has recently intensified because of randomized-observational discrepancies regarding the effect of postmenopausal hormone replacement therapy on coronary heart disease. Reanalyses of observational data that excluded prevalent users of hormone replacement therapy led to attenuated discrepancies, which begs the question of whether exclusion of prevalent users should be generally recommended. In the current study, the authors evaluated the effect of excluding prevalent users of statins in a meta-analysis of observational studies of persons with cardiovascular disease. The pooled, multivariate-adjusted mortality hazard ratio for statin use was 0.77 (95% confidence interval (CI): 0.65, 0.91) in 4 studies that compared incident users with nonusers, 0.70 (95% CI: 0.64, 0.78) in 13 studies that compared a combination of prevalent and incident users with nonusers, and 0.54 (95% CI: 0.45, 0.66) in 13 studies that compared prevalent users with nonusers. The corresponding hazard ratio from 18 RCTs was 0.84 (95% CI: 0.77, 0.91). It appears that the greater the proportion of prevalent statin users in observational studies, the larger the discrepancy between observational and randomized estimates.
Epidemiology & Infection - Current Issue
Volume 140 Issue 03
Thu, 01 Mar 2012 00:00:00 -0000
Epidemiology Infection, Volume 140 Issue 03 Epidemiology Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope includes the zoonoses, tropical infections, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections will be of particular value.
HYG volume 140 issue 3 Cover and Front matter
Miscellaneous Epidemiology & Infection, Volume 140 Issue 03, pp f1-f2Abstract
Latest Issue of International Journal of Medical Microbiology
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Cover
Fri, 03 Feb 2012 07:15:44 -0800
Editorial Board
Fri, 03 Feb 2012 07:15:44 -0800
Subscriptions
Fri, 03 Feb 2012 07:15:44 -0800
Table of contents
Fri, 03 Feb 2012 07:15:45 -0800
Anti-Mullerian Hormone: A Potential New Tool in Epidemiologic Studies of Female Fecundability
Baird, D. D., Steiner, A. Z. Fri, 03 Feb 2012 07:15:45 -0800
The objective of the present commentary is to suggest that epidemiologists explore the use of anti-Müllerian hormone (AMH) as a new measurement tool in fecundability studies. The authors briefly summarize the advantages and limitations of the 3 current approaches to studies of fecundability. All 3 approaches involve the collection of time-to-pregnancy or attempt-time data, and most are limited to participants who plan their pregnancies. AMH is produced by ovarian follicles during their early growth stages and is measured clinically to assess ovarian reserve (the number of remaining oocytes). Unlike time to pregnancy, serum AMH level can be assessed regardless of pregnancy-attempt status. Measurements are not significantly affected by phase of the menstrual cycle, oral contraceptive use, or early pregnancy. The authors suggest that AMH measurement can be a valuable addition to traditionally designed fecundability studies. In addition, this hormone should be investigated as an independent measure of fecundability in studies that focus on exposures hypothesized to target the ovary.
Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research From a Meta-Analysis of Statins
Danaei, G., Tavakkoli, M., Hernan, M. A. Fri, 03 Feb 2012 07:15:45 -0800
Randomized clinical trials (RCTs) are usually the preferred strategy with which to generate evidence of comparative effectiveness, but conducting an RCT is not always feasible. Though observational studies and RCTs often provide comparable estimates, the questioning of observational analyses has recently intensified because of randomized-observational discrepancies regarding the effect of postmenopausal hormone replacement therapy on coronary heart disease. Reanalyses of observational data that excluded prevalent users of hormone replacement therapy led to attenuated discrepancies, which begs the question of whether exclusion of prevalent users should be generally recommended. In the current study, the authors evaluated the effect of excluding prevalent users of statins in a meta-analysis of observational studies of persons with cardiovascular disease. The pooled, multivariate-adjusted mortality hazard ratio for statin use was 0.77 (95% confidence interval (CI): 0.65, 0.91) in 4 studies that compared incident users with nonusers, 0.70 (95% CI: 0.64, 0.78) in 13 studies that compared a combination of prevalent and incident users with nonusers, and 0.54 (95% CI: 0.45, 0.66) in 13 studies that compared prevalent users with nonusers. The corresponding hazard ratio from 18 RCTs was 0.84 (95% CI: 0.77, 0.91). It appears that the greater the proportion of prevalent statin users in observational studies, the larger the discrepancy between observational and randomized estimates.
American Journal of Epidemiology - recent issues
Cover
Fri, 03 Feb 2012 07:15:44 -0800
Editorial Board
Fri, 03 Feb 2012 07:15:44 -0800
Subscriptions
Fri, 03 Feb 2012 07:15:44 -0800
Table of contents
Fri, 03 Feb 2012 07:15:45 -0800
Anti-Mullerian Hormone: A Potential New Tool in Epidemiologic Studies of Female Fecundability
Baird, D. D., Steiner, A. Z. Fri, 03 Feb 2012 07:15:45 -0800
The objective of the present commentary is to suggest that epidemiologists explore the use of anti-Müllerian hormone (AMH) as a new measurement tool in fecundability studies. The authors briefly summarize the advantages and limitations of the 3 current approaches to studies of fecundability. All 3 approaches involve the collection of time-to-pregnancy or attempt-time data, and most are limited to participants who plan their pregnancies. AMH is produced by ovarian follicles during their early growth stages and is measured clinically to assess ovarian reserve (the number of remaining oocytes). Unlike time to pregnancy, serum AMH level can be assessed regardless of pregnancy-attempt status. Measurements are not significantly affected by phase of the menstrual cycle, oral contraceptive use, or early pregnancy. The authors suggest that AMH measurement can be a valuable addition to traditionally designed fecundability studies. In addition, this hormone should be investigated as an independent measure of fecundability in studies that focus on exposures hypothesized to target the ovary.
Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research From a Meta-Analysis of Statins
Danaei, G., Tavakkoli, M., Hernan, M. A. Fri, 03 Feb 2012 07:15:45 -0800
Randomized clinical trials (RCTs) are usually the preferred strategy with which to generate evidence of comparative effectiveness, but conducting an RCT is not always feasible. Though observational studies and RCTs often provide comparable estimates, the questioning of observational analyses has recently intensified because of randomized-observational discrepancies regarding the effect of postmenopausal hormone replacement therapy on coronary heart disease. Reanalyses of observational data that excluded prevalent users of hormone replacement therapy led to attenuated discrepancies, which begs the question of whether exclusion of prevalent users should be generally recommended. In the current study, the authors evaluated the effect of excluding prevalent users of statins in a meta-analysis of observational studies of persons with cardiovascular disease. The pooled, multivariate-adjusted mortality hazard ratio for statin use was 0.77 (95% confidence interval (CI): 0.65, 0.91) in 4 studies that compared incident users with nonusers, 0.70 (95% CI: 0.64, 0.78) in 13 studies that compared a combination of prevalent and incident users with nonusers, and 0.54 (95% CI: 0.45, 0.66) in 13 studies that compared prevalent users with nonusers. The corresponding hazard ratio from 18 RCTs was 0.84 (95% CI: 0.77, 0.91). It appears that the greater the proportion of prevalent statin users in observational studies, the larger the discrepancy between observational and randomized estimates.
Epidemiology & Infection - Current Issue
Volume 140 Issue 03
Thu, 01 Mar 2012 00:00:00 -0000
Epidemiology Infection, Volume 140 Issue 03 Epidemiology Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope includes the zoonoses, tropical infections, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections will be of particular value.
HYG volume 140 issue 3 Cover and Front matter
Miscellaneous Epidemiology & Infection, Volume 140 Issue 03, pp f1-f2Abstract
Latest Issue of International Journal of Medical Microbiology
Sites:
American Type Culture Collection (ATCC): ATCC is a global bioresource center that stores and distributes biological materials such as cell lines, bacteria, animal and plant viruses and antisera, fungi, protozoa, algae, clones and other molecular genomic materials. We also manage databases and offer repository management and other labora...Antimicrobial Resistance Surveillance (BSAC Working Party): Information about antimicrobial resistance surveillance programmes run by BSAC (British Society for Antimicrobial Chemotherapy) and links to related sites.
Association for Professionals in Infection Control and Epidemiology, Inc.: Association for Professionals in Infection Control and Epidemiology is an association of healthcare professionals working to reduce, control and prevent infections associated with or acquired in a healthcare setting.
Bacterial Toxins: Friends or Foes?: Overview of the biochemistry and mechanism of action of bacterial toxins from the Center for Disease Control (CDC).
Candida albicans Pseudomonas Helicobacter epidemiology: Molecular epidemiology, virulence factors, virulence genes of pathogenic microorganisms.
CDC Division of Healthcare Quality Promotion: Issues in Healthcare Settings: Articles and statistics related to infectious diseases and hospitals and hospital personnel.
Clinical Microbiology Software: Interpretation and Report of Antimicrobial Susceptibility Test.: This is based on "rule-base expert system" and freeware. End-user can modify and add rules. This is assistant software to interpret and report antimicrobial( antibiotics ) susceptibility tests for clinical microbiology department,
Common Cold: A comprehensive source of information on the common cold that facilitates informed decisions about cold prevention and treatment.
Department of Medical Microbiology of the University of Zurich: Homepage of the Department of Medical Microbiology, University Zurich
Family Practice Notebook: Infectious Disease: Covers Bacteria, Emerging, Examination, Faver, Fever, Fungus, Helminth, Immune, Immunization, Parasite, Prion, Procedure, Sexually Transmitted Disease, Travel, Vector and Virus. Related chapters from other specialties include Dermatology, Ophthalmology, Gastroenterology, HIV, Laboratory, Neurolo...
General Practice Notebook - Infectious disease: Coverage of this medical speciality.
Genomics and Bacterial Pathogenesis: This review summarises the current methodologies used in genome analysis
Global Infectious Diseases and Epidemiology Network: GIDEON - Provides information, including disease, therapy and vaccine lists, support and demo of GIDEON. Medical software for the fields of infectious diseases and microbiology targeted at doctors and lab specialists.
Infection Control: Recent litterature abstracts on infection control updated every three months
Infectious disease information: Information about infectious disease in overview form, provided by Aventis.
Know Your Enemy: Determining the Genetic Blueprint of Disease-Causing Microorganisms, NIAID Fact Sheet: A fact sheet from the National Institute of Allergy and Infectious Diseases (NIAID) explaining, in simple terms, the objectives behind the finished and ongoing sequencing projects of pathogen genomes.
Medical Microbiology Synopsis: Site provides an overview of medical microbiology for students of medicine. Typical and atypical microbial flora are listed per specimen source and characterized in flowchart diagrams that can be easily memorized.
Microbiology at Mount Sinai Hospital, Toronto, Canada: We are a comprehensive, primary-source, Canadian microbiology and infectious diseases site. This site contains data from population and laboratory based surveillance programs, frequently requested papers and protocols, our current in use Lab Manual, as well as a forum for frequently asked q...
Physiopathological role of microbial metallogeny: Page personnelle de Stephane PLOUVIER
Reservoirs of Antibiotic Resistance Network: ROAR - Alliance for the Prudent Use of Antibiotics: A network, interactive database and information source organized around antibiotic resistance.
Reviews in Medical Microbiology: Journal of the Pathological Society of Great Britain and Ireland. Covering developments and techniques in medical microbiology, virology, mycology, parasitology, clinical microbiology, and hospital infection.
The United Kingdom National Culture collection: Fireworks Splice HTML
Using DNA Microarrays to Study Host-Microbe Interactions: This article provides a detailed introduction to DNA microarray technology and their application to the identification of host-pathogen interactions and virulence factors.
This directory is based on the Open Directory and may have been modified